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| autoid | 20 |
| crg_id | CRG080500009 |
| titleoftrial | The comparative effects of Atenolol and Nebivolol on renal function in patients with Diabetic Nephropathy |
| acronymnoftrial | |
| website | http:// |
| identificationno | |
| leadprefix | Dr |
| leadsurname | Riley |
| leadgivennames | Stephen G |
| leadposition | Senior Lecturer in Nephrology |
| leaddepartment | Institute of Nephrology |
| leadorganisation | University Hospital of Wales |
| leadaddress | Heath Park, Cardiff, CF14 4XN Wales |
| leademail | rileysg@cf.ac.uk |
| leadphone | +44 2920748467 |
| leadfax | +44 2020748470 |
| leadsuffix | |
| contactprefix | |
| contactsurname | |
| contactgivennames | |
| contactposition | |
| contactdepartment | |
| contactorganisation | |
| contactaddress | |
| contactemail | |
| contactphone | |
| contactfax | |
| funding | industry |
| otherfunding | |
| fundingnameofsponsors | Menarini Inc |
| ethicsapproval | yes |
| studytype | randomised |
| studytype_other | |
| groupassignment | crossover |
| blinding_patients | no |
| blinding_investigators | yes |
| blinding_outcomes | yes |
| blinding_analysts | yes |
| proposedstart | 09/2005 |
| actualstart | |
| proposedcompletiondate | 06/2006 |
| actualcompletiondate | |
| multi_center_study | no |
| numberofcentres | |
| multi_national_study | no |
| countrycentres | Wales |
| researchquestion | Does the vasodilating beta blocker Nebivolol have positive effects on renal function when compared to Atenolol. |
| study_status_recruitment | not_yet_recruiting |
| study_status_recruitment_follow | |
| healthcarecondition | Diabetic nephropathy |
| intervention1 | Nebivolol |
| intervention2 | Atenolol |
| intervention3 | |
| intervention4 | |
| participants_gender | both |
| participants_other | adults |
| age | 18-80 |
| totalrecruitment | 15 |
| inclusion | Diabetes Proteinuria from 0.5-5g/24hr Est Creatinine clearance 35-70ml/min |
| exclusion | Poorly controlled hypertension Other known renal disease Pregnancy |
| primaryoutcomes | Isotope GFR and ERPF on Atenolol and Nebivolol |
| secondaryoutcomes | Changes in Arterial function on Atenolol and Nebivolol |
| reference |