Cochrane Renal Group

Reviews of Diagnostic Test Accuracy Studies

Information about this initiative can be found on the Cochrane Collaboration's website at http://srdta.cochrane.org/en/index.html

Register of Diagnostic Test Accuracy Studies

We have successfully submitted a proposal to the Cochrane Collaboration Steering Group for a further three years of funding for the development of the Cochrane-wide study-based register of reports of diagnostic test accuracy studies.

This exciting project will ultimately lead to better support for authors and review groups doing Cochrane systematic reviews of diagnostic test accuracy, by providing a clean and comprehensive register of potential studies for their reviews.

Searching for diagnostic test accuracy studies (DTAS) is more difficult and time consuming than for reports of randomised controlled trials. This is due to both poor reporting by the authors of these studies, and inconsistent indexing in Medline and other databases, making it difficult to develop search strategies that are both sensitive and specific i.e. that will retrieve all relevant studies without too may irrelevant records 1,2 , 3 This adds an extra burden of time for systematic review authors, who often have to screen many thousands of records to find a few relevant to their reviews.

Our objectives for the next three years include:

  • transferring the Register to a relational database
  • continuing to screen Medline records for inclusion in the Register, and to source records from Cochrane and non-Cochrane reviews of diagnostic accuracy
  • developing coding for test names and target conditions to enable accurate retrieval of studies from the register
  • continuing to develop training materials for trials search coordinators in searching for DTAS and screening search results.
  • providing support in search strategy development for the authors and trials search coordinators of pilot reviews
  • submitting a proposal to the National Library of Medicine for introducing a diagnostic test accuracy study Medline publication type e.g. diagnostic accuracy.pt.
A more detailed description of the Register can be found in Chapter 7 Section 7.3.1.3 of the Cochrane Handbook for Reviews of Diagnostic Test Accuracy at http://srdta.cochrane.org/en/authors.html

We would like to acknowledge the Screening and Test Evaluation Programme (STEP), School of Public Health, University of Sydney, for supporting the development of the register proposal.

 

1. Doust JA, Pietrzak E, Sanders S, Glasziou PP. 2005. Identifying studies for systematic reviews of diagnostic tests was difficult due to the poor sensitivity and precision of methodologic filters and the lack of information in the abstract. Journal of Clinical Epidemiology 58 (5):444-449 PM: 15845330
[PubMed abstract]

2.Leeflang M, Scholten R, Reitsma H, Rutjes A, Bossuyt P. 2006. Use of methodological search filters to identify diagnostic accuracy studies can lead to the omission of relevant studies. Journal of Clinical Epidemiology 59(3):234-40 PM: 16488353
[PubMed abstract]

3. Mitchell RL, Rinaldi F, Craig JC. 2005. Performance of published search strategies for studies of diagnostic test accuracy (SDTA) in Medline and Embase [abstract 001]. 13th Cochrane Colloquium, Melbourne, Australia, 22-26 October 2005. Program and abstracts:33

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Do you have conference proceedings [books or cd-roms] that you no longer need or could lend to us for hadsearching? If so, email Ruth Mitchell for details

Handsearching

Are you interested in helping us handsearch journals or conference proceedings. To find out more about our handsearching activities, email Ruth Mitchell