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Nephrology: Clinical Research for Nephrologists

Introduction

• Craig JC, Hawley C. Clinical research for nephrologists: a practical series. Nephrology. 2010;15(1):7

In this issue we launch a series that is aimed to provide readers with tools so that they can find, evaluate and apply clinical research to their own practice in a time-friendly and effective manner, and, might even be inspired to conduct their own research.

We have designed this series to be comprehensive, clinically relevant, and to be read and used. As well as covering the usual methods of systematic reviews, trials and diagnostic test evaluation, we have also covered newer approaches to literature searching, and important issues of economic evaluation and research transfer into practice and policy, which are usually neglected.

Each paper begins with a clinical scenario that frames the research question, and provides a framework for each paper. Most papers are short, and written with the recognition that busy clinical readers have too many other commitments and too little time to read all papers in their “would be good to read at some time”stack.

The tragedy of nephrology practice is that there has been little if any change in the poor prognosis for people with chronic kidney disease. A mortality rate of 10—15% per year for people on dialysis is simply unacceptable. If there is to be the improvement, which for the sake of these people and their families, there must be, then more and better research must occur. This series is designed to promote such research and assist nephrologists to use existing research better.

The medical literature

• Cross NB, Craig JC, Webster AC. Asking the right question and finding the right answers. Nephrology. 2010 ;15(1):8-11. [abstract]
• Webster AC, Cross NB, Mitchell R, Craig JC. How to get the most from the medical literature: searching the medical literature effectively. Nephrology. 2010;15(1):12-9. [abstract]
• Cullis J, Webster AC. How to get the most from the medical literature: keeping up to date in nephrology. Nephrology. 2010;15(3):269-76. [abstract]
• Jun M, Zoungas S, Perkovic V, Webster AC. How to read a report of a randomized controlled trial. Nephrology. 2010;15(2):153-7. [abstract]
• Palmer SC, Navaneethan SD, Strippoli GF. How to read a nephrology systematic review. Nephrology. 2010 ;15(2):158-64. [abstract]

Systematic reviews

• Henderson LK, Craig JC, Willis NS, Tovey D, Webster AC. How to write a Cochrane systematic review. Nephrology. 2010;15(6):617-24. [abstract]
• Palmer SC, Navaneethan SD, Strippoli GF. How to read a nephrology systematic review. Nephrology. 2010 ;15(2):158-64. [abstract]
• Hodson EM, Craig JC. How to apply results from randomized trials and systematic reviews to individual patient care. Nephrology. 2010;15(3):277-80. [abstract]

Applying evidence

• Gallagher MP, Cass A, Craig JC. Applying evidence into routine clinical care at a unit level: the exemplar of renal anaemia management. Nephrology. 2010;15(4):429-33. [abstract]

Ecomic evaluations

• Wong G, Howard K, Craig JC. Economic evaluation in clinical nephrology: Part 1. An introduction to conducting an economic evaluation in clinical practice. Nephrology. 2010;15(4):434-40. [abstract]
• Wong G, Howard K, Craig JC. Economic evaluation in clinical nephrology: part 2. Applying economic evaluations in clinical nephrology. Nephrology. 2010;15(5):533-9. [abstract]

Randomized controlled trials

• Kelly PJ, Webster AC, Craig JC. How many patients do we need for a clinical trial? Demystifying sample size calculations. Nephrology. 2010;15(8):725-31. [abstract]
• Navaneethan SD, Palmer SC, Smith A, Johnson DW, Strippoli GF. How to design a randomized controlled trial. Nephrology. 2010;15(8):732-9. [abstract]
• Smith A, Palmer S, Johnson DW, Navaneethan S, Valentini M, Strippoli GF. How to conduct a randomized trial. Nephrology. 2010;15(8):740-6. [abstract]
• Hodson EM, Craig JC. How to apply results from randomized trials and systematic reviews to individual patient care. Nephrology. 2010;15(3):277-80. [abstract]

Diagnostic test accuracy studies

• Williams GJ, Craig JC. What nephrologists need to know about diagnostic test accuracy articles. Nephrology. 2010;15(5):540-3. [abstract]

Prognostic studies

• Palmer SC, Strippoli GF. How to read critically a prognostic cohort study. Nephrology. 2010;15(7):676-82. [abstract]

Introduction to writing
a Cochrane systematic review:
Sydney workshops 2012
[Details]

Are you interested in writing a review?

Contact us for potential review titles!

Help us with our Renal Trials Register

Do you have conference proceedings [books or cd-roms] that you no longer need or could lend to us for hadsearching? If so, email Ruth Mitchell for details

Handsearching

Are you interested in helping us handsearch journals or conference proceedings. To find out more about our handsearching activities, email Ruth Mitchell